High quality visualization of biochemical pathways in BioPath

نویسنده

  • Falk Schreiber
چکیده

Biochemical reactions form large and complex networks. Comprehensible visual representations of these networks help biochemists understand the relationships between the chemical components. Typically pathway diagrams are manually produced drawings. Because of the steady progress of knowledge and the complex relationships in these networks, automatic visualizations are necessary. Bio-Path is a system for the exploration and automatic visualization of biochemical pathways. It has been developed to obtain an electronic version of the well-known Boehringer Biochemical Pathways poster and offers new possibilities to find information and to navigate through pathways. BioPath has a specific database containing reactions and a hierarchical clustering of reactions and reaction networks. One feature is the automatic generation of pathways from the database and their high quality visualization. This paper states the requirements for the visualization of biochemical pathways, presents a layout algorithm and shows how BioPath can be used to explore biochemical reaction networks.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

High quality visualization of

Biochemical reactions form large and complex networks. Comprehensible visual representations of these networks help biochemists understand the relationships between the chemical components. Typically pathway diagrams are manually produced drawings. Because of the steady progress of knowledge and the complex relationships in these networks, automatic visualizations are necessary. BioPath is a sy...

متن کامل

The system architecture of the BioPath system

BioPath is a prototype system for the interactive exploration of biochemical pathways. It has been developed as an electronic version of the famous Boehringer Biochemical Pathways map and offers various ways to access information on substances and pathways and to navigate through pathways. This paper describes the main features and the software architecture of BioPath. The companion paper [11] ...

متن کامل

BioPath

Fig. 1. Example Biochemical processes in organisms are considered as very large networks consisting of reactants, products and enzymes with interconnections representing reactions and regulation. Examples are given by the well known Boehringer poster [4] and the Biochemical Pathways atlas [5]. These networks are very complex and grow fast by the steady progress of knowledge in life sciences. Bi...

متن کامل

Biochemical Pathways

The famous Biochemical Pathways wall chart has been converted into a reaction database. The web based retrieval system C@ROL has been interfaced to this BioPath database providing a wide variety of search methods for chemical structures, enzymes, and reactions that can allow one to explore the endogenous metabolism of different species. The database has been made accessible on the internet at: ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • In silico biology

دوره 2 2  شماره 

صفحات  -

تاریخ انتشار 2002